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Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics

Dino Luethi, Matthias E. Liechti

The International Journal of Neuropsychopharmacology May 24, 2018 DOI: 10.1093/ijnp/pyy047 (opens in new tab)

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AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Serotonin
Keywords Pharmacology Monoamine neurotransmitter Dopamine transporter Serotonin transporter Potency Norepinephrine transporter In vitro Intrinsic activity Receptor
Key findings Rapid assessment of in vitro pharmacological profiles of new psychoactive substances can help predict psychoactive doses and effects in humans and facilitate appropriate scheduling.

Abstract

The rapid assessment of in vitro pharmacological profiles of new psychoactive substances can help to predict psychoactive doses and effects in humans and facilitate the appropriate scheduling of new psychoactive substances.

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