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Psilocybin use in bipolar disorder: A comprehensive review

André Do, Laurence Cloutier, Lydia Hébert‐tremblay, Christel Thauvin

Journal of Affective Disorders October 31, 2025 DOI: 10.1016/j.jad.2025.120485 (opens in new tab)

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AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Psilocybin
Keywords Depression economics Hallucinogen Bipolar disorder Bipolar illness Value mathematics Medline Psychotherapist
Citations 1
Key findings The efficacy and safety of psilocybin for bipolar depression remain unclear, and more research is needed to clarify its therapeutic value.

Abstract

Despite its promising potential, the efficacy and safety of psilocybin in the treatment of BD depression remain unclear, and future research is essential to clarify its therapeutic value in BD.

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