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The psychedelic renaissance: can psilocybin possibly combat depression?

Hamna Raheel, Unaiza Naeem, Asim Shaikh, Omer Ahmed Shaikh

International Journal of Surgery Global Health November 1, 2022 DOI: 10.1097/gh9.0000000000000089 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Peer reviewed
Topics Anxiety Depression Psilocybin
Keywords Mental health Depression economics Population Psychological intervention Clinical psychology Hallucinogen Mood
Key points The text states that the COVID-19 pandemic increased major depressive disorder cases by 27.6% and anxiety disorder cases by 25.6%, with an estimated 137.1 and 116.1 additional disability-adjusted life years per 100,000 population, respectively, attributed to these conditions during the period.

Abstract

Mental health disorders such as depression and anxiety are major contributors to the overall global health burden. COVID-19 has further aggravated mental health disorders and also increased substance abuse due to lockdowns1. The Global Burden of Disease reported that the pandemic has led to a 27.6% increase in cases of major depressive disorder (MDD) and a 25.6% increase in cases of anxiety disorders2. An estimated 137.1 (95% UI: 92.5–190.6) additional disability-adjusted life years per 100 000 population for MDD and 116.1 per 100,000 population (95% UI: 79.3–163.80) for anxiety disorders have been incurred, as well, during this period3.

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