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Taking psilocybin for science

Devon Stoliker, Adeel Razi

October 10, 2022 DOI: 10.54377/d188-22e2 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort
Sample size 60
Population Healthy volunteers
Intervention Psilocybin
Topics Psilocybin
Keywords Hallucinogen
Key findings Brain scans of healthy volunteers during a psilocybin experience reveal neural changes that may inform mental health treatment development.

Abstract

Sixty healthy volunteers took magic mushrooms in a lab, and scientists recorded their brains during their experience. Approximately half of the Australian population will experience a mental health disorder during their lifetime, and scientists are turning to an unlikely place in the search for treatment. Researchers at Monash University are scanning the brains of healthy […]

Comparable studies

Other observational and cohort studies on psilocybin, most cited first.

Study Year Design Participants
Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression 2017 Observational cohort n = 19
Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels Healthy volunteers 2019 Observational cohort n = 8
Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin Humans 2017 Observational study
Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population. USA adult respondents from the National Survey on Drug Use and Health (2008-2012) 2015 Observational cohort n = 190,000
Prediction of Psilocybin Response in Healthy Volunteers Healthy volunteers 2012 Observational cohort n = 409

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