Neural correlates of the personality factor openness before and after psilocybin-therapy to depressed patients
Zenodo (CERN European Organization for Nuclear Research) August 31, 2019 DOI: 10.5281/zenodo.7796283 (opens in new tab) via OpenAlex
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | Individuals with treatment-resistant depression |
| Intervention | Psilocybin-assisted intervention |
| Topics | Psilocybin |
| Keywords | Openness to experience Clinical psychology Psychotherapist Personality |
| Key findings | Changes in openness to experience are associated with neural correlates that may mediate clinical improvements following psilocybin-assisted therapy. |
Abstract
This document is my Master's Thesis for the Research Master Cognitive Neuroscience program at Maastricht University. The present study investigated the relationship between openness and its neural correlates in treatment-resistant depression preceding and following a psilocybin-assisted intervention, to (i) extent the findings of personality neuroscience from healthy to depressed population and (ii) unfold the neural mechanisms that could be mediating clinical improvements.