Chemical Constituents ofGymnopilus spectabilisand Their Antioxidant Activity
In‐kyoung Lee, Sung‐min Cho, Soon‐ja Seok, Bong‐sik Yun
Mycobiology 2008 DOI: 10.4489/myco.2008.36.1.055 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Keywords | Mushroom Dpph Antioxidant Abts Superoxide radical Traditional medicine Botany Food science |
| Citations | 32 |
| Key findings | Bisnoryangonin and hispidin from Gymnopilus spectabilis displayed significant antioxidant activity against ABTS, DPPH, and superoxide radicals, while the other two compounds did not. |
Abstract
Gymnopilus spectabilis, a hallucinogenic mushroom belonging to the family Cortinariaceae, is found growing in dense clusters on stumps and logs of hardwoods and conifers. It contains the hallucinogenic alkaloid psilocybin and its strongly bitter taste makes it undesirable as an edible. In an effort to identify chemical constituents of Korean native wild mushrooms, 4,6-decadiyne-1,3,8-triol (1), ergosta-4,6,8(14), 22-tetraen-3-one (2), bisnoryangonin (3), and hispidin (4) were isolated from the methanolic extract of the fruiting bodies of G. spectabilis. Their structures were assigned on the basis of various spectroscopic studies. Compounds 3 and 4 displayed significant scavenging activity against the ABTS radical cation, DPPH radical, and superoxide radical anion, while 1 and 2 exhibited no antioxidant activity.