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EXPRESSION OF CONCERN: Efficacy of psilocybin for treating symptoms of depression: systematic review and meta-analysis

BMJ May 4, 2024 DOI: 10.1136/bmj.q1025 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Meta-analysis Randomized Peer reviewed
Population Adults with depression
Intervention Psilocybin
Topics Psilocybin Depression
Keywords Meta-analysis Depression economics Clinical trial Clinical psychology Psychotherapist Hallucinogen
Citations 2
Key findings A calculation error in standardised mean differences likely overestimated the benefits of psilocybin for depression.

Abstract

The journal and the authors are investigating the problem.The study analysed data from randomised trials of psilocybin for the treatment of depression in adults.A methodological concern has been raised about an error in the calculation of standardised mean differences.This is likely to have overestimated the benefits of psilocybin.The authors are reviewing and responding to the error and its implications for the findings and conclusions of the paper.The authors' response will be reviewed by The BMJ who will decide what further action is needed.

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