The effect of particular active substances of hallucinogenic mushrooms
Marek Wieczorek
Acta Universitatis Lodziensis Folia Biologica et Oecologica November 26, 2014 DOI: 10.2478/fobio-2014-0014 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Psilocybin Serotonin |
| Keywords | Hallucinogen Ibotenic acid Muscimol Pharmacology |
| Citations | 4 |
| Key findings | Psilocybin, psilocin, ibotenic acid, and muscimol affect brain neurochemistry by mimicking serotonin and GABA, leading to hallucinations and influencing emotion and mental health. |
Abstract
Magic mushrooms have accompanied man for thousands of years. Formerly they were used for religious and culture purposes. Those fungi belong mainly to the genera Conocybe, Copelandia, Panaeolus, Psilocybe and Stropharia. A number of these fungal species produce substances, like psilocybin, psilocin, ibotenic acid or muscimol. Because of their chemical similarity to naturally occurring neurotransmitters like serotonin and GABA these substances, after ingestion, affect brain neurochemistry and by this induce hallucinations. This mini review presents the influence of psilocybin, psilocin, ibotenic acid and muscimol on the nervous system. Also the effects of the above mentioned substances on emotion and mental health of people are discussed.
Comparable studies
Other narrative reviews on serotonin, most cited first.
Citations in the library
Cited by 3
- Toxicological and pharmacological profile of Amanita muscaria (L.) Lam. – a new rising opportunity for biomedicine Pharmacia November 26, 2020
- Amanita muscaria: Ecology, Chemistry, Myths Encyclopedia September 2, 2021
- Psychoactive Isoxazoles, Muscimol, and Isoxazole Derivatives from the Amanita (Agaricomycetes) Species: Review of New Trends in Synthesis, Dosage, and Biological Properties. International journal of medicinal mushrooms 2023
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and 5 more in the library