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MDMA ("ecstasy") and neurotoxicity.

Michael C Mithoefer, Lisa Jerome, Richard Doblin, George A. Ricaurte

Science June 1, 2003 DOI: 10.1126/science.300.5625.1504 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics MDMA
Keywords MDMA Research Ecstasy studies MDMA Science Drug research Psychedelic research Neurotoxicity Brain damage Nerve toxicity Serotonin depletion Neurotoxic effects Human studies Clinical research Human observations Patient studies Clinical trials Human data Brain serotonin Serotonin system Neurotransmitters Serotonergic effects Brain chemistry
Citations 36
Key findings MDMA use is associated with lasting changes in the serotonin system suggestive of neurotoxicity, but definitive causal evidence in humans is limited.

Abstract

MDMA ("ecstasy") and neurotoxicity.