The Effects of Mindfulness-Based Interventions in People with Parkinson's Disease: A Systematic Review and Meta-Analysis.
Mo Yi, Wenmin Zhang, Baosheng Zhao, Zhiwen Wang
Clinical Gerontologist 2025 DOI: 10.1080/07317115.2024.2314192 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review and meta-analysis Peer reviewed |
|---|---|
| Population | Patients with Parkinson's disease |
| Intervention | Mindfulness-based interventions |
| Topics | Meditation |
| Keywords | Meta-analysis Parkinson’s disease Motor symptoms Psychological symptom Quality of life Systematic review |
| Citations | 10 |
| Key findings | Mindfulness-based interventions significantly improve depression, anxiety, mindfulness, and quality of life in Parkinson's disease patients, but do not significantly affect motor symptoms. |
Abstract
To examine the effectiveness of mindfulness-based interventions (MBIs) on psychological symptoms, motor symptoms, and quality of life in patients with Parkinson's disease (PD). Published studies in Chinese and English languages, conducted from inception to March 2023, were identified by searching PubMed, Web of Science, Cochrane Library, CINAHL, PsycINFO, and two Chinese electronic databases. The systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta Analyses guidelines. Twelve studies were selected for quantitative syntheses. The impact of MBIs on reducing depression and anxiety, and improving mindfulness and quality of life in PD patients was statistically significant compared to the control group. However, no statistically significant effect on motor symptoms was observed. Subgroup analysis indicated that participants from Asia, those who received face-to-face sessions, and those whose sessions lasted 1.5 hours showed a more positive effect than other subgroups. Patients with PD may benefit from MBIs to improve psychological symptoms and quality of life. MBIs represent a pivotal non-pharmacological therapeutic approach in clinical practice. MBIs confer positive improvements in psychological well-being and quality of life in PD patients. However, it remains challenging to conclusively determine their efficacy in addressing motor symptoms.
Comparable studies
Other systematic reviews and meta-analyses on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations | 2014 | Meta-analysis | n = 3,515 |
| Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects | 2009 | Systematic review and meta-analysis | |
| The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators | 2012 | Meta-analysis | n = 163 |
| Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission | 2016 | Meta-analysis of individual patient data from randomized controlled trials | n = 1,258 |
| Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials | 2011 | Systematic review |
Citations in the library
Cited by 2
- Effects of Meditation and Yoga on Anxiety, Depression and Chronic Inflammation in Patients with Parkinson's Disease: A Randomized Clinical Trial. Psychotherapy and Psychosomatics 2025
- Effectiveness of mindfulness meditation on balance, cognitive functions, quality of life, and falls prevention in Parkinson's disease: A systematic review. Neuropsychological rehabilitation September 7, 2026
Cites 20
- The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology 2003
- How Does Mindfulness Meditation Work? Proposing Mechanisms of Action From a Conceptual and Neural Perspective Perspectives on Psychological Science October 14, 2011
- A qualitative analysis of mindfulness‐based cognitive therapy (MBCT) in Parkinson's disease Psychology and Psychotherapy Theory Research and Practice October 20, 2009
- Mindfulness-based stress reduction in Parkinson’s disease: a systematic review BMC Neurology May 15, 2017
- The impact of a mindfulness-based stress reduction program on university students' mental health: A mixed-methods evaluation. Journal of American College Health December 2024
and 15 more in the library