IUPHAR-review: The integration of classic psychedelics into current substance use disorder treatment models.
David B. Yaden, Andrea P Berghella, Peter S. Hendricks, Mary E. Yaden, Michael Levine, Julia S Rohde, Sandeep M. Nayak, Matthew W Johnson, Albert Garcia‐romeu
Pharmacological Research 2024 DOI: 10.1016/j.phrs.2023.106998 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Addiction Psilocybin Psychedelic-assisted therapy |
| Keywords | Medication assisted treatment Psychedelics Addiction treatment Substance abuse recovery Mental health innovations Medical research |
| Citations | 12 |
| Key findings | Classic psychedelic-assisted therapies can be integrated into most mainstream evidence-based SUD treatments currently used in clinical settings. |
Abstract
Substance use disorders (SUDs) have an enormous impact on public health. With classic psychedelic-assisted therapies showing initial promise in treating multiple SUDs, it is possible that these treatments will become legally available options for patients with SUDs in the future. This article highlights how classic psychedelic-assisted therapies might be integrated into current clinical practice. We first describe contemporary evidence-based treatments for SUDs and highlight how classic psychedelic-assisted therapies might fit within each treatment. We suggest that classic psychedelic-assisted therapies can be integrated into most mainstream evidence-based SUD treatments that are currently used in clinical settings, indicating broad compatibility of classic psychedelics with contemporary SUD treatment paradigms.
Comparable studies
Other narrative reviews on psilocybin for addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. General population | 2019 | Integrative review | |
| Psychedelics as anti-inflammatory agents Animal models and cellular studies | 2018 | Review | |
| Psychedelic Drugs in Biomedicine | 2017 | Review | |
| DARK Classics in Chemical Neuroscience: Psilocybin | 2018 | Review | |
| Psilocybin for treating substance use disorders? | 2016 | Narrative review |