Designing a meditation module to affect etiological and preventive factors in primary hypertensive patients-A pilot study.
Kapila Goswami Sharma, S D Manjula, Shobha U Kamath, M Mukhyaprana Prabhu, M G Ramesh Babu, Ujjal Bose, K Vasanthalaxmi
Physiological reports February 1, 2025 DOI: 10.14814/phy2.70226 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pilot study Randomized Peer reviewed |
|---|---|
| Sample size | 9 |
| Population | Primary hypertensive patients |
| Intervention | meditation module |
| Duration | 5 days a week for 4 weeks |
| Topics | Meditation |
| Keywords | Brain‐derived neurotrophic factor Essential hypertension Meditation based intervention Primary hypertensive patients |
| Citations | 1 |
| Key points | The designed meditation module was valid, feasible, and improved biochemical (BDNF) and psychological parameters (anxiety, stress, emotional quotient, mental state, sleep quality, quality of life, happiness) in primary hypertensive patients. |
Abstract
The aim of the present pilot study is to design, validate, and check the feasibility and efficacy of the designed meditation module on etiological and preventive factors in primary hypertensive patients (PHP). The systematic and detailed meditation module was formulated to prevent the complications of hypertension. The designed module was validated by 5 subject experts in the field of complementary and alternative therapy and research. Content Validity Ratio (CVR), Average Congruency Percentage (ACP), and Content Validity Index were calculated. The intervention was given for 5 days a week for 4 weeks, to 9 PHP to check the feasibility and the efficacy of the module by analyzing biochemical and psychological parameters. A randomized controlled trial is planned ahead with this module as intervention. The designed meditation module had 19 concepts with CVR >0.49 and ACP > 90% which were retained, 2 were modified (CVR 0.6, ACP 80) and 1 was deleted as CVR was <0.49 and ACP < 70%. The feasibility test mean was 93.33 ± 8.66 and the efficacy was tested by increase in the brain-derived neurotrophic factor (BDNF) (p = 0.022) and decrease in anxiety (p = 0.022) and perceived stress (p = 0.016), improvement in emotional quotient (p = 0.011), mental state (p = 0.044), quality of sleep (p = 0.001), quality of life (p = 0.011), and happiness state (p = 0.003). The designed meditation module was found valid by the experts, feasible to patients, and efficient in improving biochemical and psychological parameters among PHP to affect the hypertensive etiological factors and check the progress and complications of the disorder. Trial Registration: CTRI/2022/09/045421.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cites 21
- Meditation Programs for Psychological Stress and Well-being JAMA Internal Medicine January 6, 2014
- The effect of mindfulness meditation on sleep quality: a systematic review and meta‐analysis of randomized controlled trials Annals of the New York Academy of Sciences December 21, 2018
- Mindfulness-Based Blood Pressure Reduction (MB-BP): Stage 1 single-arm clinical trial PLoS One November 27, 2019
- Consciousness, self-consciousness, and meditation Phenomenology and the Cognitive Sciences April 18, 2008
- Impact of a Stress Reduction, Meditation, and Mindfulness Program in Patients with Chronic Heart Failure: A Randomized Controlled Trial. Arquivos brasileiros de cardiologia October 1, 2023
and 16 more in the library