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[Migraine with multiple visual symptoms and out-of-body experience may mimic epilepsy].

Kyoko Hosokawa, Kiyohide Usami, Shunsuke Kajikawa, Akihiro Shimotake, Yoshihisa Tatsuoka, Akio Ikeda, Ryosuke Takahashi

Rinsho shinkeigaku = Clinical neurology August 30, 2021 DOI: 10.5692/clinicalneurol.cn-001577 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population An 18-year-old man with visual symptoms, out-of-body experience, and headache attacks
Intervention Valproic acid
Dose small dose
Keywords Epilepsy Migraine Out-of-body experience Visual symptoms
Citations 1
Key findings Out-of-body experience can occur as a rare aura in migraine and should be distinguished from epilepsy.

Abstract

The patient was an 18-year-old man who had suffered from various visual symptoms as follows since he was 17 years old: 1) a diagonal line appeared in his visual field, shifting his upper field of view to the right and his lower field of view to the left; 2) his whole vision seemed distorted with ripples; and 3) black spots covered parts of his visual field and moved up and down. These visual symptoms were followed by out-of-body experience (OBE), which he felt as seeing his own body apart from his left back. Headache attacks followed these symptoms. On brain MRI, bilateral occipital atrophy was suspected. An electroencephalogram showed intermittent irregular delta in the bilateral occipital area. No epileptiform discharges were observed. We finally diagnosed him as having migraine with multiple visual auras and OBE. He was very well treated with a small dose of valproic acid which he tolerated well. OBE rarely occurs in migraine and should be distinguished from epilepsy.