Online Mindfulness-Based Intervention (eMBI) in management of dyspnea in patients with interstitial lung disease: A randomized clinical trial.
Siliana Maria Duarte Miranda, Sara de Pinho Cunha Paiva, Luiz Fernando Ferreira Pereira, Gabriela Patrus Ananias De Assis Pires, Andrew Nogueira Albuquerque Leal, Giane Amorim Ribeiro-Samora, Eliane Viana Mancuzo
Complementary Therapies in Medicine December 1, 2024 DOI: 10.1016/j.ctim.2024.103106 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Prospective, open-label, controlled trial Randomized Peer reviewed |
|---|---|
| Sample size | 49 |
| Population | Adults with interstitial lung disease and mMRC dyspnea score ≥ 1 |
| Intervention | Online Mindfulness-Based Intervention (eMBI) |
| Duration | 8-week intervention |
| Topics | Meditation |
| Keywords | Pulmonary fibrosis Quality of life |
| Citations | 3 |
| Key findings | A greater proportion of patients who completed an eight-week online mindfulness-based intervention showed reduced dyspnea compared with the control group (48.9% vs. 15.4%). |
Abstract
Dyspnea and cough are frequent symptoms in ILD patients. The management of these symptoms is challenging, and evidence-based therapies are lacking. To evaluate the effect of an online Mindfulness-Based Intervention (eMBI) on reducing dyspnea in patients affected by different ILDs. This study was a prospective, open-label, controlled trial that included patients ≥18 years and a modified Medical Research Council (mMRC) dyspnea scale score of ≥ 1. Patients were randomized into either the eMBI or the control group (CG) for 8 weeks. The primary outcome was the change in the dyspnea mMRC scale. The Leicester Cough Questionnaire (LCQ), King's Brief Interstitial Lung Disease (K-BILD) questionnaire, and Depression, Anxiety, and Stress Scale (DASS-21) were performed before and after the eight weeks. All analyses were conducted on an intention-to-treat basis. The study was registered at the Brazilian Registry of Clinical Trials (ReBEC), RBR-3s4mf9y. 24 patients in the eMBI and 25 in the CG completed the intervention. In the eMBI group, compared to the control group, there was a greater proportion of patients with a reduction in dyspnea according to the mMRC scale score (48.9 % versus, 15.4 %, p = 0.001). There was no significant difference between the groups in the LCQ (p = 0.666), or in the K-BILD (p = 0.108), depression (p = 0.08), or anxiety (p = 0.869 or stress (p = 0.789). No moderate or severe adverse events were observed in either group. Eight weeks eMBI is a potentially viable and safe approach, that can help manage dyspnea in ILD patients.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cites 6
- Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders American Journal of Psychiatry July 1, 1992
- Mindfulness on Symptom Control and Quality of Life in Patients in Palliative Care: A Systematic Review. The American journal of hospice & palliative care July 19, 2023
- Online mindfulness-based cognitive therapy for fatigue in patients with sarcoidosis (TIRED): a randomised controlled trial. The Lancet Respiratory Medicine November 1, 2022
- Stay mindfully active during the coronavirus pandemic: a feasibility study of mHealth-delivered mindfulness yoga program for people with Parkinson's disease. BMC Complementary Medicine and Therapies February 7, 2022
- Understanding changes in dyspnoea perception in obstructive lung disease after mindfulness training. BMJ open respiratory research 2018
and 1 more in the library