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The Effect of Mindfulness-Based Cognitive Therapies on Sexual Function, Sexual Distress, and Depression in Women: A Meta-Analysis Study.

Ayşe Çuvadar, Handan Özcan

International journal of sexual health : official journal of the World Association for Sexual Health 2025 DOI: 10.1080/19317611.2024.2414064 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Meta-analysis Peer reviewed
Population Women
Intervention mindfulness-based cognitive therapies
Topics Depression Meditation
Keywords Sexual dysfunction Mindfulness-based cognitive therapy Sexual distress
Citations 3
Key findings Mindfulness-based cognitive therapies are effective in improving sexual function and reducing sexual distress and depression in women.

Abstract

Objective: This study was carried out to determine the effect of mindfulness-based cognitive therapies adapted for sexual function concerns on women's sexual function, sexual distress, and depression levels.

Methods: For this meta-analysis study, a review was conducted by screening studies published in the last 10 years on PubMed, Web of Science, EBSCOhost, Google Scholar, and YÖK National Thesis Center databases from February to May 2024. After this initial review, 11 studies were included in this study. Considering the study design, quality assessment tools developed by JBI were used to evaluate the risk of bias. CMA version 2 was used for data synthesis. Data were synthesized using meta-analysis and narrative synthesis methods.

Results: In this meta-analysis, mindfulness-based cognitive therapies were found to be effective in improving sexual function in women, and a high level of heterogeneity was detected among studies (standardized mean difference [SMD] = 0.461, 95% confidence interval [CI] = 0.163 to 0.760; Z = 3.027, p = .002, I2 = 79.083). Additionally, it was also determined that mindfulness-based cognitive therapies were effective in reducing sexual distress in women (SMD = -0.352, 95% CI = -0.638 to -0.066; Z= -2.412, p = .016, I2 = 78.377). Finally, mindfulness-based cognitive therapies were also determined to be effective in reducing symptoms of depression in women (SMD = -0.217, 95% CI = -0.420 to -0.015; Z= -2.101, p = .036, I2 = 27.688).

Conclusions: Mindfulness-based cognitive therapies were found to be effective in decreasing women's sexual dysfunction and reducing levels of sexual distress and depression.

Comparable studies

Other systematic reviews and meta-analyses on depression, most cited first.

Study Year Design Participants
Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression Participants with major depression in placebo-controlled, double-blind, randomized... 2015 Systematic review and meta-analysis
Side-effects associated with ketamine use in depression: a systematic review. Patients with depression 2018 Systematic review
Comparative efficacy of racemic ketamine and esketamine for depression: a systematic review and meta-analysis Adults with unipolar or bipolar major depression 2020 Systematic review and meta-analysis n = 1,877
Single-dose infusion ketamine and non-ketamine N-methyl-D-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories Patients with major depressive disorder or bipolar depression 2016 Systematic review and meta-analysis n = 588
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188

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