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Effect of technology-supported mindfulness-based interventions for maternal depression: a systematic review and meta-analysis with implementation perspectives for resource-limited settings.

Bekelu Teka Worku, Misra Abdulahi, Demissew Amenu, Bruno Bonnechère

BMC Pregnancy and Childbirth February 13, 2025 DOI: 10.1186/s12884-025-07286-9 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review with meta-analysis Peer reviewed
Sample size 2,481
Population Pregnant and postpartum women with maternal depression
Intervention technology-supported mindfulness-based interventions
Topics Depression Meditation
Keywords Maternal depression Meta-analysis Mindfulness-based interventions Perinatal depression Postpartum depression Prenatal depression Systematic review Technology
Citations 9
Key findings Technology-supported mindfulness-based interventions had a positive effect on maternal depression, with a standardized mean difference of -0.55.

Abstract

Maternal depression is pregnancy and childbirth-related depression during pregnancy (prenatal depression (PND)) or after delivery (postpartum depression (PPD)). It is a recognized global public health concern with extensive repercussions adversely affecting women's well-being and the developmental progress of infants. Mindfulness-based interventions (MBIs) have been shown to be effective in maternal depression. Technology-supported MBI could be an effective preventive strategy for maternal depression, especially in low- and middle-income countries (LMICs) where lack of important resources limits the accessibility to standard care. However, the limited available studies assessing the effect of technology-supported MBIs for maternal depression might be insufficient to reach a definitive conclusion. This systematic review aimed to evaluate the pooled estimated effect of technology-supported MBIs for maternal depression, identify available studies, and reveal applicable health technologies with MBIs. This study was conducted according to the PRISMA-P 2020 and the review protocol was registered in PROSPERO; CRD42024537853. The risk of bias was evaluated using the PEDro scale. The meta-analysis was done with R. Data from 18 articles, none from low-income countries (LICs), were included in the systematic review, representing 2,481 participants, 15 studies were included in the meta-analysis. The pooled effect size indicated that technology-supported MBIs had a positive effect on maternal depression (SMD - 0.55, 95% CI [- 0.70; -0.40], p < 0.001). The sub-group analysis showed that this intervention was effective in both PND (SMD = - 0.57, 95% CI [- 0.74; -0.39], p < 0.001) and PPD (SMD - 0.53, 95% CI [- 0.91; -0.15], p = 0.014). Integrating technology-supported MBIs into maternal care is recommended to enhance maternal mental health. However, the lack of trials in LMICs may limit the generalizability and external validity of this finding and it is crucial to conduct further research, in the area to tailor intervention and maximize its effectiveness. Context-specific trial studies are pivotal for successful program adoption.

Comparable studies

Other systematic reviews and meta-analyses on depression, most cited first.

Study Year Design Participants
Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression Participants with major depression in placebo-controlled, double-blind, randomized... 2015 Systematic review and meta-analysis
Side-effects associated with ketamine use in depression: a systematic review. Patients with depression 2018 Systematic review
Comparative efficacy of racemic ketamine and esketamine for depression: a systematic review and meta-analysis Adults with unipolar or bipolar major depression 2020 Systematic review and meta-analysis n = 1,877
Single-dose infusion ketamine and non-ketamine N-methyl-D-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories Patients with major depressive disorder or bipolar depression 2016 Systematic review and meta-analysis n = 588
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188

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