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Effects of Mindfulness Therapy on Breast Cancer Patients with Depression or Anxiety: A Systematic Review and Meta-analysis.

Jingjing Yan, Fenhua Wang, Xianghua Yu

Actas Españolas de Psiquiatría March 1, 2025 DOI: 10.62641/aep.v53i2.1949 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review and meta-analysis Randomized Peer reviewed
Sample size 1,823
Population Breast cancer patients
Intervention mindfulness therapy
Topics Anxiety Depression Meditation
Citations 3
Key findings Mindfulness therapy significantly reduces anxiety and depressive symptoms in breast cancer patients, with no significant difference based on intervention type or duration.

Abstract

Breast cancer (BC) is the most common malignant tumor threatening women's health globally, with rising incidence rates and significant psychological impacts, particularly in China, where the prevalence of depressive and anxious mood disorders among BC patients is notably higher than the global average. To evaluate the effect of mindfulness therapy on anxiety and depressive symptoms in breast cancer patients, as psychological distress significantly affects their quality of life and often persists despite medical treatment. A computerized search of Web of Science, PubMed, ScienceDirect, Cochrane Library, and Embase databases was conducted for randomized controlled trials involving the effects of positive thinking interventions on anxiety and depressive symptoms in breast cancer patients. The search was conducted from the time of database construction to December 2023. Two researchers completed literature screening, data extraction, and quality assessment, and then analyzed using RevMan 5.4 software. A total of 15 studies involving 1823 patients were included. Meta-analysis results demonstrated that anxiety scores [mean difference (MD) = -0.67, 95% CI (-1.05, -0.29), p = 0.0005] and depression scores [MD = -2.26, 95% CI (-2.91, -1.61), p 8 weeks vs ≤8 weeks) had little effect on the improvement of patients' depression and anxiety scores. The distribution of studies was unsymmetrical, and there was a certain degree of publication bias. This study provides scientific evidence and practical guidance for psychological care in breast cancer patients, supporting the effectiveness of mindfulness-based interventions (excluding mindfulness-based cognitive therapy (MBCT)) in alleviating anxiety and depression. Future research should focus on high-quality randomized controlled trials to confirm and expand these findings and explore more effective intervention strategies.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

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