Skip to content

The Role of Mindfulness in Reducing Depression During COVID-19 At-home Treatment.

Geurim Go, Su Young Lee, Chan-Hyung Kim, Jhin Goo Chang

Disaster medicine and public health preparedness April 16, 2025 DOI: 10.1017/dmp.2025.82 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional survey with mediation analysis Peer reviewed
Sample size 380
Population COVID-19 patients undergoing at-home treatment in February to April 2022
Topics Depression Meditation
Keywords Fear of covid-19 Isolation Stress
Key findings Mindfulness partially mediates the relationship between fear of COVID-19 and depression, accounting for 32.3% of the total effect.

Abstract

Mindfulness is a promising psychological resource that can alleviate dysfunctional fear responses and promote mental health. We investigated how mindfulness affects fear and depression in isolated patients with coronavirus disease 2019 (COVID-19), and whether it acts as a mediator. We conducted an online survey of COVID-19 patients undergoing at-home treatment from February to April 2022. The survey included a questionnaire on fear of COVID-19 (measured by the Fear of COVID-19 Scale), mindfulness (measured by the Mindful Attention Awareness Scale), and depression (measured by the Patient Health Questionnaire). A total of 380 participants completed the questionnaire. We analyzed the correlation between each variable and performed a mediation analysis using hierarchical regression and bootstrapping to verify the statistical significance of the mediating effects. Each variable was significantly correlated. Hierarchical regression analysis showed that the association between the fear of COVID-19 and depression decreased from 0.377-0.255, suggesting that mindfulness partially mediates the relationship between fear of COVID-19 and depression. Bootstrapping analysis showed that the indirect effect of the mediating variable (mindfulness) is 0.121, which accounts for 32.3% of the total effect. Interventions that promote mindfulness in patients with acute COVID-19 may be beneficial for their mental health.

Comparable studies

Other cross-sectional and survey studies on depression, most cited first.

Study Year Design Participants
Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. International sample of people who reported having used a psychedelic 2020 Cross-sectional survey n = 985
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. Adults who used 5-MeO-DMT in a group setting with structured procedures 2019 Cross-sectional survey n = 362
Psychological and neuropsychological assessment of regular hoasca users. Regular hoasca users from a U.S. branch of União do Vegetal and matched non-user controls 2016 Cross-sectional study n = 57
Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers Self-selected microdosers and non-microdosers recruited via a mobile application 2021 Cross-sectional survey n = 8,703
Effects of Naturalistic Psychedelic Use on Depression, Anxiety, and Well-Being: Associations With Patterns of Use, Reported Harms, and Transformative Mental States. Adults with at least one lifetime psychedelic experience 2022 Cross-sectional survey n = 2,510

Citations in the library

Explore topics