Advancements in Psychoactive Alkaloid Delivery, Neuroenhancement, and Psychedelic Therapies: Exploring the Frontiers of Modern Pharmacology
ACS Medicinal Chemistry Letters May 8, 2024 DOI: 10.1021/acsmedchemlett.4c00181 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Psilocybin Psychedelic-assisted therapy |
| Keywords | Transdermal Pharmacology Neurostimulation Tryptamine Hallucinogen |
| Citations | 2 |
| Key findings | Innovations in transdermal formulations, neuroenhancement, intravenous infusion of psilocybin or psilocin, and crystalline tryptamine derivatives represent significant progress in drug delivery systems and therapeutic use of psychedelic compounds. |
Abstract
This Patent Highlight explores advancements in pharmacology, focusing on the novel delivery and application of psychoactive substances. It highlights the development of transdermal formulations for psychoactive alkaloids, neuroenhancement techniques to augment emotional responses, and the intravenous infusion of psilocybin or psilocin for various therapeutic purposes. Additionally, it delves into the characterization and potential uses of crystalline forms of tryptamine derivatives. These innovations signify significant progress in drug delivery systems, neurostimulation methods, and the therapeutic use of psychedelic compounds, potentially revolutionizing the treatment of psychological and neurological disorders.
Comparable studies
Other narrative reviews on psilocybin, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. General population | 2019 | Integrative review | |
| The pharmacology of psilocybin | 2002 | Review | |
| Serotonin research: contributions to understanding psychoses | 2008 | Review | |
| Psychedelics, Meditation, and Self-Consciousness | 2018 | Review | |
| The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act | 2018 | Review |
Citations in the library
Cites 6
- Safety and risk assessment of psychedelic psychotherapy: A meta-analysis and systematic review. Psychiatry Research May 1, 2024
- The mechanistic divide in psychedelic neuroscience: An unbridgeable gap? Neurotherapeutics January 25, 2024
- Who are you after psychedelics? A systematic review and a meta-analysis of the magnitude of long-term effects of serotonergic psychedelics on cognition/creativity, emotional processing and personality Neuroscience & Biobehavioral Reviews February 3, 2024
- Psychedelic Therapy: A Primer for Primary Care Clinicians-Psilocybin. American Journal of Therapeutics
- From taboo to treatment: The emergence of psychedelics in the management of pain and opioid use disorder. British Journal of Clinical Pharmacology December 1, 2024
and 1 more in the library