Skip to content

Nat Neurosci

ISSN 1097-6256; 1546-1726;

2 papers in the library · 291 citations · publishing 2022-2025

Papers

Sort Most recent Most cited

The neural basis of psychedelic action.

Nat Neurosci October 24, 2022 Alex C. Kwan, David E. Olson, Katrin H. Preller et al. 291 citations

Psychedelics are serotonin 2A receptor agonists that can lead to profound changes in perception, cognition and mood. In this review, we focus on the basic neurobiology underlying the action of psychedelic drugs. We first discuss chemistry, highlighting the diversity of psychoactive molecules and the principles that govern their potency and pharmacokinetics. We describe the roles of serotonin...