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Annals of medicine and surgery (2012)

ISSN 2049-0801

4 papers in the library · 9 citations · publishing 2025-2026

Papers

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Advancing treatment paradigms: the role of psilocybin in managing major depressive disorder.

Annals of medicine and surgery (2012) 2026 Sana Rasheed, Rida Arif, Ahmed Asad Raza et al. 1 citation

Psilocybin, a naturally occurring psychedelic compound, has received attention as a novel therapeutic option for major depressive disorder (MDD), particularly in cases where traditional treatments prove ineffective. The study aims to evaluate psilocybin's therapeutic potential by examining its efficacy, safety, and mechanisms of action as well as addressing the societal and regulatory...

Safety considerations and risk mitigation strategies for ketamine use: a comprehensive review.

Annals of medicine and surgery (2012) May 1, 2025 Reem Sayad, Ahmed Saad Elsaeidy, Amna M Anis et al. 7 citations

Ketamine, a dissociative anesthetic, has gained widespread use in various medical contexts, including anesthesia, pain management, and treatment-resistant depression. Despite its therapeutic potential, concerns regarding its safety profile have prompted ongoing research and regulatory guidance. This comprehensive literature review explores the current safety considerations of ketamine,...

Assessment of laparotomy-induced stress response in opium- and morphine-addicted rats by measuring serum glucose and corticosterone levels: an animal experiment.

Annals of medicine and surgery (2012) March 1, 2025 Yeganeh Pakbaz, Sepideh Eydivandi, Ayda Khandani et al. 1 citation

Surgical procedures induce stress responses similar to severe illnesses, activating the metabolic and neuroendocrine systems, especially the hypothalamic-pituitary-adrenal (HPA) axis. The resulting cortisol surge maintains homeostasis but can adversely affect recovery by elevating blood glucose levels and increasing the risk of complications. Given the high prevalence of opium use, especially...