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Online Publication Service of Würzburg University (Würzburg University)

2 papers in the library · publishing 2024-2026

Papers

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A Randomized Controlled Trial of Psilocybin for the Treatment of Obsessive-Compulsive Disorder

Online Publication Service of Würzburg University (Würzburg University) 2026 Katja Ehrmann

Obsessive Compulsive Disorder (OCD) is a prevalent mental disorder, with a lifetime prevalence of 2-3%, characterized by intrusive thoughts (obsessions) and repetitive behaviors (compulsions). These thoughts and behaviors take up a significant amount of time, cause immense distress, and compromise the quality of life of those who suffer from OCD. In addition to psychological factors such as...

One- and Two-Photon Excitable Photoswitchable Orthoand Allosteric Ligands of Class A GPCRs

Online Publication Service of Würzburg University (Würzburg University) January 30, 2024 Hubert Georg Lambert Gerwe

Photopharmacology is a vivid field of research that combines the unsurpassed spatiotemporal resolution of light with the principles of pharmacology. By introduction of synthetic chemical photoswitches into the structures of biologically active compounds, researchers can obtain control over biological processes. This is especially useful in the research of G protein-coupled receptors (GPCRs)...