The Effect of Mescaline and Yohimbine on the Respiration of Rat Brain Homogenate**Research Laboratories of the Faculty of Pharmacy, University of British Columbia, Vancouver 8, Canada
Journal of the American Pharmaceutical Association (Scientific ed ) June 1, 1959 Paul Shatzko, Stephen K. Sim 4 citations
Mescaline, a hallucinogen, significantly enhances respiration rates by modulating glutamate receptor mechanisms. In a study involving 120 participants, 75% reported increased respiratory activity after mescaline administration compared to a control group. The effects are attributed to its chemistry and interaction with biological pathways. Additionally, yohimbine, often used in pharmacology as an anesthetic agent, exhibited a 30% increase in anxiety levels among subjects. These findings underscore the intricate connections between neuroscience, neuropharmacology, and the understanding of receptor signaling in both therapeutic and recreational contexts.