A comprehensive survey of hallucinogenic plants and their chemical constituents, this work catalogs the botanical sources, historical uses, and active compounds of known psychedelic substances. The authors, a renowned ethnobotanist and the chemist who first synthesized LSD, document over 453 references and include 78 photographs and line drawings. They describe the distribution, preparation, and cultural roles of these plants across societies, alongside the chemical structures and pharmacological properties of their alkaloids and other psychoactive molecules. The text serves as a foundational reference for the interdisciplinary study of hallucinogens, linking traditional knowledge with modern chemistry.
Third wave therapies such as mindfulness and Acceptance and Commitment Therapy (ACT) show preliminary value for treating alcohol use disorders (AUDs). A systematic review of 17 studies found that both therapies are better than no treatment or treatments with minimal efficacy, and some evidence suggests they are comparable to effective psychosocial treatments for AUDs. ACT and mindfulness may offer an alternative for patients who have not responded to or disengaged from standard treatments, and they may also help with co-occurring mental health conditions. However, more research with randomized controlled designs, larger samples, and longer follow-ups is needed to confirm their utility.