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New Zealand Medical Journal

ISSN 1175-8716

2 papers in the library · publishing 2023-2025

Papers

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Reappraisal of the hype and hope offered by psilocybin treatment of depression

New Zealand Medical Journal September 15, 2025 Ben Beaglehole, Jenni Manuel

aim: To provide a balanced account of psilocybin treatment of depression for expectations to be appropriately set. method: Review and discussion of key psilocybin efficacy studies. Reporting of side effects and risk of harm with psychedelic treatments. Comparisons and contrasts with ketamine studies of treatment-resistant depression (TRD). result: Early psilocybin studies offer promise but...