PCN reports : psychiatry and clinical neurosciences
December 1, 2025
Fumiya Miyano, Nobuyuki Mitsui, Yutaka Fujii et al.
Kitousei-Seishinbyo, or psychosis induced by invocation, was first described by Morita in 1915 as a culture-bound syndrome characterized by possession-like states and personality transformation triggered by prayer or spiritual practices. New psychosocial triggers (e.g., self-improvement seminars, emerging religious groups) have been identified. However, reports of possession-related episodes...
PCN reports : psychiatry and clinical neurosciences
December 1, 2025
Akihiro Koreki, Masataka Kaji, Hiroki Oi et al.
Delusional misidentification of the self is a rare psychotic symptom in which individuals misidentify themselves. These symptoms are sometimes accompanied by psychotic renaming, reflecting profound psychological changes in the self. To date, such symptoms have not been fully understood through the lens of the minimal self, especially with respect to the sense of agency (SoA). We report the case...
PCN reports : psychiatry and clinical neurosciences
September 1, 2025
Itsuki Terao, Takahiro Tsuge, Tomoo Sato et al.
2 citations
Although electroconvulsive therapy (ECT) is the standard treatment for Stage 2 or higher treatment-resistant depression, it has several drawbacks. Repetitive transcranial magnetic stimulation (rTMS) and intravenous racemic ketamine (IV ketamine) have emerged as potential alternatives, but their comparative effectiveness and safety remain unclear due to limited evidence. We systematically...
PCN reports : psychiatry and clinical neurosciences
March 1, 2025
Daniel Greer, Jennifer Atherton, Justina Girgis
Delta-9-tetrahydrocannabiphorol (Δ9-THCP) is a potent phytocannabinoid found naturally in the cannabis plant in small quantities. This cannabinoid is noted to potently bind to cannabinoid receptor 1 and cannabinoid receptor 2 and is reported to be highly psychoactive. A small amount of Δ9-THCP is found naturally, which led to its isolation and synthetic production. This isolate is beginning to...
PCN reports : psychiatry and clinical neurosciences
December 1, 2024
Yasuhito Nagai, Yuko Tajima, Koichi Miyakawa
Dextromethorphan (DXM) is an over-the-counter drug that is commonly abused by teenagers. Its main pharmacological property is a low-affinity N-methyl-d-aspartate (NMDA) receptor antagonist. We report acute psychotic dissociation induced by DXM and alcohol in a patient with alcohol dependence, which made it difficult to distinguish alcohol withdrawal symptoms with limited information. The...
PCN reports : psychiatry and clinical neurosciences
September 1, 2024
Jaylyn Thompson, David F Lo, Alexis Foschini et al.
1 citation
The aim of this study was to explore the use of perinatal ketamine to see if it can be used for the reduction of postpartum depression (PPD) following cesarean section (C-section). PubMed, Cochrane, and Web of Science were the primary databases used for this review. Search terms used on January 5, 2024 incorporated "ketamine," "C-section," "postpartum depression," and related synonyms. The...
PCN reports : psychiatry and clinical neurosciences
December 1, 2023
Simon Ruffell, Max Crosland-Wood, Rob Palmer et al.
37 citations
Ayahuasca is a psychedelic plant brew originating from the Amazon rainforest. It is formed from two basic components, the Banisteriopsis caapi vine and a plant containing the potent psychedelic dimethyltryptamine (DMT), usually Psychotria viridis. Here we review the history of ayahuasca and describe recent work on its pharmacology, phenomenological responses, and clinical applications. There...
PCN reports : psychiatry and clinical neurosciences
September 1, 2023
Chisato Tanaka, Kenta Wakaizumi, Akira Ninomiya et al.
3 citations
The coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented stress. Mindfulness-based interventions (MBIs) are known to be effective in reducing stress. However, it is unclear how long-term outcomes differ between those who continue mindfulness practice after MBIs and those who do not. In this study, we hypothesized that those who continued mindfulness practice would have higher...