Comparative study: trimetazidine versus olanzapine on cognitive dysfunction and behavioral changes in ketamine-induced psychosis model in mice
The Egyptian Journal of Neurology Psychiatry and Neurosurgery April 29, 2025 Yosra M. Magdy, Sherif A. Kamar, Hoda A. Fansa et al.
Mitochondrial dysfunction and oxidative stress may contribute to schizophrenia. Negative symptoms and cognitive dysfunction in individuals with schizophrenia are resistant to anti-psychotic medications, but physical exercise is an effective treatment. Exercise’s beneficial effects involve releasing irisin from skeletal muscle by activating mitochondrial peroxisome proliferator-activated...