J Psychopharmacol
February 28, 2019
David Erritzøe, James Smith, Patrick M. Fisher et al.
95 citations
Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers.
J Psychopharmacol
February 15, 2018
Robin Carhart-Harris, Leor Roseman, Eline Haijen et al.
646 citations
Psychedelic drugs are making waves as modern trials support their therapeutic potential and various media continue to pique public interest. In this opinion piece, we draw attention to a long-recognised component of the psychedelic treatment model, namely ‘set’ and ‘setting’ – subsumed here under the umbrella term ‘context’. We highlight: (a) the pharmacological mechanisms of classic...
J Psychopharmacol
December 1, 2016
David Nutt
19 citations
Psilocybin for anxiety and depression in cancer care? Lessons from the past and prospects for the future.
J Psychopharmacol
December 1, 2016
Psycho-existential distress in cancer patients: A return to "entheogens".
J Psychopharmacol
November 15, 2016
Classic hallucinogens share pharmacology as serotonin 5-HT 2A , 5-HT 2B , and 5-HT 2C receptor agonists. Unique among most other Schedule 1 drugs, they are generally non-addictive and can be effective tools in the treatment of addiction. Mechanisms underlying these attributes are largely unknown. However, many preclinical studies show that 5-HT 2C agonists counteract the addictive effects of...
J Psychopharmacol
July 19, 2010
Michael C Mithoefer, Mark T Wagner, Ann T Mithoefer et al.
672 citations
The safety and efficacy of {+/-}3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study.
J Psychopharmacol
July 8, 2010
Procedural and declarative memory task performance, and the memory consolidation function of sleep, in recent and abstinent ecstasy/MDMA users.
J Psychopharmacol
March 20, 2009
MDMA (ecstasy) use is associated with reduced BOLD signal change during semantic recognition in abstinent human polydrug users: a preliminary fMRI study.
J Psychopharmacol
July 1, 2008
1,191 citations
There has recently been a renewal of human research with classical hallucinogens (psychedelics). This paper first briefly discusses the unique history of human hallucinogen research, and then reviews the risks of hallucinogen administration and safeguards for minimizing these risks. Although hallucinogens are relatively safe physiologically and are not considered drugs of dependence, their...