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J Psychopharmacol

ISSN 0269-8811; 1461-7285;

34 papers in the library · 4,078 citations · publishing 2008-2026

Papers

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Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers.

J Psychopharmacol February 28, 2019 David Erritzøe, James Smith, Patrick M. Fisher et al. 95 citations

Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers.

Psychedelics and the essential importance of context.

J Psychopharmacol February 15, 2018 Robin Carhart-Harris, Leor Roseman, Eline Haijen et al. 646 citations

Psychedelic drugs are making waves as modern trials support their therapeutic potential and various media continue to pique public interest. In this opinion piece, we draw attention to a long-recognised component of the psychedelic treatment model, namely ‘set’ and ‘setting’ – subsumed here under the umbrella term ‘context’. We highlight: (a) the pharmacological mechanisms of classic...

The serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens.

J Psychopharmacol November 15, 2016

Classic hallucinogens share pharmacology as serotonin 5-HT 2A , 5-HT 2B , and 5-HT 2C receptor agonists. Unique among most other Schedule 1 drugs, they are generally non-addictive and can be effective tools in the treatment of addiction. Mechanisms underlying these attributes are largely unknown. However, many preclinical studies show that 5-HT 2C agonists counteract the addictive effects of...

The safety and efficacy of {+/-}3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study.

J Psychopharmacol July 19, 2010 Michael C Mithoefer, Mark T Wagner, Ann T Mithoefer et al. 672 citations

The safety and efficacy of {+/-}3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study.

Human hallucinogen research: guidelines for safety.

J Psychopharmacol July 1, 2008 1,191 citations

There has recently been a renewal of human research with classical hallucinogens (psychedelics). This paper first briefly discusses the unique history of human hallucinogen research, and then reviews the risks of hallucinogen administration and safeguards for minimizing these risks. Although hallucinogens are relatively safe physiologically and are not considered drugs of dependence, their...