Attenuation of the Neuropsychiatric Effects of Ketamine With Lamotrigine
Archives of General Psychiatry March 1, 2000 Amit Anand, Dennis S. Charney, Dan A. Oren et al. 425 citations
BACKGROUND: The cognitive, behavioral, and mood effects of N-methyl-D-aspartate (NMDA) receptor antagonists, such as phencyclidine and ketamine, have been used to study the effects of NMDA receptor dysfunction. Pharmacological modulation of the effects of NMDA receptor antagonists, such as ketamine, may lead to development of novel therapeutic agents for psychiatric illnesses such as...