Serotonin 5-HT2C Receptor Signaling Analysis Reveals Psychedelic Biased Agonism.
ACS Chemical Neuroscience September 13, 2025 Emma M. Bonniwell, Rana Alabdali, Joseph J. Hennessey et al. 3 citations
The serotonin 2C receptor (5-HT 2C ) is a G protein-coupled receptor implicated in multiple physiological and psychological processes and has been investigated as a therapeutic target for neuropsychiatric conditions such as obesity, drug abuse, and depression. With renewed interest in serotonergic psychedelics for treating depression, 5-HT 2C may contribute to psychedelic-induced therapeutic...
DOI: 10.1021/acschemneuro.5c00647 (opens in new tab)
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Psychedelics
Hallucinogens
Entheogens
Mind-altering drugs
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