Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.
Sci Rep October 13, 2017 Robin Carhart-Harris, Leor Roseman, Mark Bolstridge et al. 590 citations
Psilocybin with psychological support is showing promise as a treatment model in psychiatry but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and blood oxygen-level dependent (BOLD) resting-state functional connectivity (RSFC) were measured with functional magnetic resonance imaging (fMRI) before and after treatment with psilocybin (serotonin agonist) for...