Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants.
Neuropsychopharmacology October 1, 2023 Laura Ley, Friederike Holze, Denis Arikci et al. 127 citations
Mescaline, lysergic acid diethylamide (LSD), and psilocybin are classic serotonergic psychedelics. A valid, direct comparison of the effects of these substances is lacking. The main goal of the present study was to investigate potential pharmacological, physiological and phenomenological differences at psychoactive-equivalent doses of mescaline, LSD, and psilocybin. The present study used a...
DOI: 10.1038/s41386-023-01607-2 (opens in new tab)
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Psychedelics
Hallucinogens
Comparative drug research
Pharmacology