The blueprint of human functional architecture shifts from cognition to anatomy during perturbations of consciousness
bioRxiv Preprint Server June 7, 2026 Andrea I. Luppi, Dragana Manasova, Justine Y. Hansen et al. preprint
Consciousness and cognition arise from the ongoing interactions between brain regions. Synchronous fluctuations of fMRI signals may indicate that two brain regions perform similar cognitive functions, but neural interactions are also constrained by anatomical connectivity and regions’ molecular, cytoarchitectonic, and metabolic profiles. Here we disentangle the respective contributions of...