Efficacy of Ketamine Infusion for Treatment of Opioid Use Disorder in Patients with Chronic Pain: a Narrative Review.
Current Pain and Headache Reports December 15, 2025 Alan D. Kaye, Madison C Wolf, Sarah I Dufour et al. 2 citations
Chronic pain and opioid use disorder (OUD) are highly prevalent and frequently co-occurring conditions that pose complex treatment challenges. While opioids are effective for pain management, prolonged use significantly enhances risk of developing substance dependence. Conversely, addiction-focused therapies often fail to relieve persistent somatic pain. Ketamine, an N-methyl-D-aspartate (NMDA)...
DOI: 10.1007/s11916-025-01437-5 (opens in new tab)
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Opioid use disorder
Addiction treatment
Analgesia
Chronic pain
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