The biosynthetic origin of psychoactive kavalactones in kava
bioRxiv Preprint Server April 4, 2018 Tomáš Pluskal, Michael P. Torrens-Spence, Timothy R. Fallon et al. 3 citations preprint
For millennia, humans have used plants for medicinal purposes. However, our limited understanding of plant biochemistry hinders the translation of such ancient wisdom into modern pharmaceuticals1. Kava (Piper methysticum) is a medicinal plant native to the Polynesian islands with anxiolytic and analgesic properties supported by over 3,000 years of traditional use as well as numerous recent...