Molecular mechanisms of rapid-acting antidepressants: New perspectives for developing antidepressants
Pharmacological Research June 26, 2023 Tao Chen, Ling Cheng, Jingwen Ma et al. 48 citations
Major depressive disorder (MDD) is a chronic relapsing psychiatric disorder. Conventional antidepressants usually require several weeks of continuous administration to exert clinically significant therapeutic effects, while about two-thirds of the patients are prone to relapse of symptoms or are completely ineffective in antidepressant treatment. The recent success of the N-methyl-D-aspartic...
DOI: 10.1016/j.phrs.2023.106837 (opens in new tab)
Ketamine
Psilocybin
Antidepressant
Nmda receptor
+2