Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders
Translational Perioperative and Pain Medicine June 29, 2022 Joseph Cichon, Renyu Liu, Hoang-Vinh Le
While the hallucinogenic plant Salvia divinorum has been safely consumed by humans for centuries for religious or recreational purposes without long-term side effects, its active component, salvinorin A, and molecular mechanism of action were not known until recently [1]. Notably, salvinorin A is a potent kappa opioid receptor (KOR) agonist that is highly selective for KOR without significant...