Comparative efficacy and acceptability of pharmacological interventions for postpartum depression: a systematic review and network meta-analysis.
Psychiatry Research July 1, 2026 Yao Xiao, Ping Xie, Danlei Li et al.
Pharmacological treatment for postpartum depression (PPD) have mainly involved conventional antidepressants, RCTs have also evaluated rapid-acting glutamatergic agents, neuroactive steroids, hormonal therapies, and botanical preparations. An updated comparative synthesis of these treatments is therefore needed. To synthesize RCT evidence and compare the efficacy, response, remission,...
DOI: 10.1016/j.psychres.2026.117318 (opens in new tab)
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Brexanolone
Medication-based interventions
Network meta-analysis
Postpartum depression
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