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Suma Jacob

3 papers in the library · 106 citations · publishing 2014-2016

Papers

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Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration.

Psychoneuroendocrinology December 2016 Sunday M. Francis, Matthew G. Kirkpatrick, Harriet de Wit et al.

The neuropeptide oxytocin (OT) has received increased experimental attention for its putative role in both normal social functioning and several psychiatric disorders that are partially characterized by social dysfunction (e.g., autism spectrum disorders: ASD). Many human experimental studies measure circulating plasma levels of OT in order to examine the relationship between the hormone and...

Effects of MDMA and Intranasal oxytocin on social and emotional processing.

Neuropsychopharmacology June 2014 Matthew G. Kirkpatrick, Royce Lee, Margaret C. Wardle et al.

MDMA (± 3,4-methylenedioxymethamphetamine, 'ecstasy') is used recreationally, reportedly because it increases feelings of empathy, sociability, and interpersonal closeness. One line of evidence suggests that MDMA produces these effects by releasing oxytocin, a peptide involved in social bonding. In the current study, we investigated the acute effects of MDMA and oxytocin on social and emotional...

Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans

Psychoneuroendocrinology April 19, 2014 M. Kirkpatrick, Sunday M. Francis, Royce Lee et al. 106 citations

MDMA (±3,4-methylenedioxymethamphetamine, ‘ecstasy’) is reportedly used recreationally because it increases feelings of sociability and interpersonal closeness. Prior work suggests that the pro-social effects of MDMA may be mediated by release of oxytocin. A direct examination of plasma levels of oxytocin after acute doses of oxytocin and MDMA, in the same individuals, would provide further...