Global Perspectives on CNS Drug Innovation: Achievements, Barriers, and Priorities for the Next Decade
The International Journal of Neuropsychopharmacology May 5, 2026 Hiroyuki Uchida, Gabriella Gobbi, Joseph Zohar et al.
BACKGROUND: Over the past decade, neuropsychopharmacology has shifted from stagnation to momentum, with first-in-class mechanisms and biomarker-enabled trials spanning psychiatry and neurology. METHODS: We narratively synthesized advances from 2013 to 2026 across central nervous system (CNS) discovery and development, including pivotal trials, regulatory actions, digital/real-world evidence,...
DOI: 10.1093/ijnp/pyag023 (opens in new tab)
Neuropsychopharmacology
Mandate
Neuroactive steroid
Clinical neuroscience
+5