Evaluating the Abuse Potential of Lenabasum, a Selective Cannabinoid Receptor 2 Agonist.
The Journal of pharmacology and experimental therapeutics October 18, 2024 Rachel Luba, Gabriela Madera, Rebecca Schusterman et al. 2 citations
Endocannabinoids, which are present throughout the central nervous system (CNS), can activate cannabinoid receptors 1 and 2 (CB1 and CB2). CB1 and CB2 agonists exhibit broad anti-inflammatory properties, suggesting their potential to treat inflammatory diseases. However, careful evaluation of abuse potential is necessary. This study evaluated the abuse potential of lenabasum, a selective CB2...