Pharmacotherapeutic Management of Depression in Patients With Cancer: A Review of Mechanistic and Clinical Evidence.
Cancer Reports May 1, 2026 Sepideh Hajivalizadeh, Kimia Farahmand, Kimia Kazemzadeh et al.
Depression is a prevalent comorbidity in cancer, yet conventional treatments show inconsistent efficacy. This review sought to provide a mechanism-based framework for managing cancer-related depression by exploring its unique pathophysiology and evaluating promising pharmacotherapies based on their alignment with these biological pathways. This narrative review synthesized evidence on promising...
DOI: 10.1002/cnr2.70587 (opens in new tab)
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Major depressive disorder
Antidepressant
Clinical trial
Comorbidity
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