The article proposes ten essential ethical points for the practice of psychedelic-assisted psychotherapy (PAP): respecting legal frameworks for psychotropic drugs, managing psychedelics safely (storage, production, security), reporting adverse effects to authorities, guaranteeing psychotherapeutic follow-up, ensuring patient safety during treatment, basing indications on scientific evidence, separating personal recreational use from medical use, avoiding proselytizing or poor medical practices, not equating personal psychedelic consumption with clinical competence, and ensuring equitable and reasonable access to care.
Psychedelic Assisted Psychotherapy (PAP) with LSD and psilocybin has been legally available in Switzerland since 2014 under supervised exceptional medical use. At Geneva University Hospital, a PAP protocol for treatment-resistant patients with depression, anxiety, and addiction combines preparation, dosing, and integration sessions within a cognitive behavioral therapy framework. Preliminary data from pre-post validated questionnaires show symptom reduction. The authors conclude that PAP is safe and useful, applicable routinely in a hospital setting for various diagnoses with treatment-resistant patients.