Adverse clinical effects associated with the use of synthetic cannabinoids: A systematic review.
Drug and Alcohol Dependence July 1, 2025 Mariana M Prete, Gabriel T B Feitosa, Maria A T Ribeiro et al. 13 citations
Synthetic cannabinoids (SCs) are potent agonists of CB1 and CB2 receptors, with affinities approximately 100 times greater than that of natural cannabis. This increased potency is associated with severe clinical outcomes, including psychosis, dependence, and various autonomic disturbances, such as seizures and rhabdomyolysis. The objective of this study was to synthesize the existing literature...