A biopsychosocial model of MDMA-assisted therapy in application: Dyadic One Session Treatment for specific phobia
Frontiers in Psychiatry September 5, 2025 Nicholas J. Ahari, Gregory A. Fonzo
3,4-methelenedioxymethamphetamine (MDMA) can be effective in treating posttraumatic stress disorder (PTSD) in controlled trials, potentially secondary to MDMA’s effects on neural circuits implicated in fear and reward. Although anxiety, stress, and fear-based disorders involve maladaptation of the neural circuits processing fear, threat, and reward, no studies have tested MDMA’s therapeutic...