Ketamine Use in Critically Ill Patients: Insights into Depressive Symptoms and Hemodynamic Changes.
Journal of Intensive Care Medicine April 16, 2026 Vrutti Patel, Saurabh Sujanyal, Lekhya Raavi et al.
BackgroundKetamine has demonstrated efficacy in treatment-resistant depression, primarily in psychiatric or outpatient populations. Its use in ICU patients remains underexplored, with limited data beyond case reports and small series. This study evaluated the association between subanesthetic ketamine infusions and improvement in depressive symptoms and hemodynamic changes in ICU...