The NEO-FFI domain of openness to experience moderates ketamine response in treatment resistant depression.
Journal of Affective Disorders 2020 Roman M. Dale, Kelly A. Bryant, Nora Finnegan et al. 17 citations
There are many putative mechanisms by which ketamine has its effect and many unanswered questions about risks and benefits of long-term ketamine therapy. A research imperative is the identification of predictors of response to intravenous ketamine, especially a sustained response to maintenance ketamine. Temperament is an inherited aspect of personality and is a predictive factor for outcome in...
DOI: 10.1016/j.jad.2019.09.010 (opens in new tab)
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Ketamine
Openness to experience
Temperament
Treatment resistant depression