Personality profiles and trauma history in ketamine therapy for mood and anxiety disorders: A latent profile analysis of short-term outcomes.
Psychopharmacology October 27, 2025 Nina Gregoire, Ethan Klukas, Kimberley Kaseweter et al.
Ketamine-assisted therapy is emerging as a fast-acting intervention for treatment-resistant depression and anxiety. However, individual response to treatment varies, and little is known about how personality traits and trauma history influence outcomes. This study investigated whether distinct personality profiles emerge in a real-world sample of patients undergoing ketamine therapy and...