Potential Antidepressive Effects of R-ketamine in Patients with Treatment Resistance Depression
Carleton undergraduate journal of science. May 16, 2025 Sumika Egner
Ketamine has a long history as an anesthetic but has recently demonstrated antidepressant effects at sub-anesthetic doses (Matveychuk et al., 2020). For individuals with treatment-resistant depression (TRD), typical antidepressants are frequently ineffective, whereas ketamine’s unique mechanisms have demonstrated promising results in reducing depressive symptoms where other treatments have...