Treatment-resistant depression (TRD) remains a major therapeutic challenge in psychiatry, affecting a substantial proportion of individuals diagnosed with major depressive disorder and contributing significantly to the overall burden of mental illness. Despite decades of research and the availability of numerous antidepressant agents, many patients fail to achieve full remission, which...
Cannabis is one of the most widely used psychoactive substances globally. In several countries, including Canada, the Netherlands, certain U.S. states, and Australia, its possession is legal. With its growing popularity in recent years, the impact of cannabis on mental health has become a focal point of numerous scientific studies. The aim of this review was to summarize the current...